Proton Pump Function in Gastric Acid Secretion
The proton pump plays a critical role for gastric acid {secretion|. The pump hydrochloric acid pump is an integral membrane protein situated on the apical surface of parietal cells in the stomach lining. It drives the active passage of protons (H+) from the cytoplasm of parietal cells into the gastric lumen, ultimately to the lowering of the stomac